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Doctors for treatment of Osteomyelofibrosis
More than 30 doctors of different specialties and directions ready to help you
Viola Fox
Germany, Solingen
Clinic: Municipal Clinic Solingen
Total work experience: 14 years
Doctor's specialization
Panayotis Kaloyannidis
United Arab Emirates, Abu Dhabi
Clinic: Burjeel Medical City
Total work experience: 27 years
Doctor's specialization
Alessandro Aiuti
Italy, Milan
Clinic: San Raffaele Hospital
Total work experience: 25 years
Doctor's specialization
Manas Kalra
India, Delhi
Clinic: Apollo Hospitals
Total work experience: 23 years
Doctor's specialization
Vikas Dua
India, Delhi, Gurgaon
Clinic: Fortis Hospitals
Total work experience: 18 years
Doctor's specialization
Kang Hyoung Jin
Republic of Korea, Seoul
Total work experience: 21 years
Doctor's specialization
Betul Tawil
Turkey, Ankara, Antalya, Istanbul
Clinic: Memorial Hospitals
Total work experience: 28 years
Doctor's specialization
Yasemin Altuner Torun
Turkey, Ankara, Istanbul, Samsun
Clinic: LIV Hospitals
Total work experience: 27 years
Doctor's specialization
10 doctors of 30
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Doctors for the treatment of osteomyelofibrosis
Frequently Asked Questions
what are the symptoms of osteomyelofibrosis
- Weakness,
- Bleeding and long-term wound healing,
- Left abdominal pain and enlarged spleen,
- Decreased vision,
- Decreased appetite,
- The appearance of fluid in the abdominal cavity,
- Edema of the lower extremities,
- Changes in the blood test
What are the complications of osteomilofibrosis
- Kidney stone disease,
- Pyelonephritis,
- Nephrosclerosis,
- Gout,
- Bleeding,
- Development of acute myeloid leukemia
Why do patients often choose osteomyelofibrosis treatment abroad
- This is a very rare pathology, occurs in approximately 1: 100,000 people. Therefore, it is better to treat it in specialized centers, since most doctors (both diagnosticians and clinicians) do not have clinical experience in the treatment of osteomyelofibrosis.
- The success rate of bone marrow transplantation in the hematology departments of Turkey, Germany, Israel and Spain is ten times higher than in the CIS.
- If additional methods of treatment are required, techniques are used that are not available in the domestic space — operations on the Da Vinci robot, which is much less traumatic than open and laparoscopic surgical interventions, proton therapy as a more effective and safe alternative to radiation therapy, and so on.
Methods of diagnosis and treatment of osteomyelofibrosis according to the world standards of 2021
How to diagnose osteomyelofibrosis
- The first diagnostic procedure is a general blood test, which most often
determines changes in the number of red blood cells and platelets. - Then a trepanobiopsy is performed (this is a type of biopsy in which a column ofcells is taken from the desired area, after which it is prepared accordingly andexamined under a microscope) of the bone marrow with molecular and cytogenetic studies of the material taken. V617F mutations of the JAK2 (in ≈60 %), CALR (in 25-35%), and MPL(in 4-8%) genes are studied.
Instead of a diagnosis of «osteomyelofibrosis», they may be mistakenly diagnosed with
- Acute leukemia,
- Multiple myeloma,
- Hodgkin`s disease,
- Chronic benzene poisoning
What are the modern methods of treatment of osteomyelofibrosis in modern
foreign clinics
- The only option in which the patient can achieve a complete cure is
allotransplantation (transplantation from a donor) of bone marrow. - As auxiliary methods, experienced doctors use the targeted drug ruxolitinib, as well as hydroxyurea, melfan, busulfan, cladribine or human interferon, sometimes they also perform splenectomy.
Also, in parallel with the main treatment, doctors conduct symptomatic treatment of anemia, pain syndrome, thrombocytopenia and other possible complications. - Some patients can be left under observation without special treatment. Health assessment is carried out using special scales for patients with low — risk osteomilofibrosis-IPSS, DIPSS or DIPSS plus.
